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| Tesofensine Powder |
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| C17H23Cl2NO |
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| 195875-84-4 |
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Tesofensine (TE) inhibits the presynaptic reuptake of the neurotransmitter¡¯s noradrenaline,dopamine and serotonin.Other types of selective serotonin reuptake inhibitors are used to treat depression and eating disorders,but they have generally failed to produce sustained weight loss.Sibutramine,in addition to its effect on serotonin,also inhibits the reuptake of other monoamines and has been shown to enhance postprandial satiety,reduce total calorie intake and to diminish the decline in energy expenditure usually associated with a diet-induced negative energy balance.
Tesofensine (TE) was originally studied for its effect on Parkinson¡¯s and Alzheimer¡¯s.Unfortunately,its exploration for these indications were limited because the patients were starting to lose too much weight.Since then,tesofensine has been studied as a way to treat obesity via its ability to reduce appetite.TE indirectly stimulates the cholinergic system and showed to be more successful than average weight loss remedies .
Tesofensine increases near transmission of a reuptake inhibitor 3 monoaminergic neurotransmitters in the brain.These neurotransmitters are serotonin,norepinephrine,and dopamine which help regulate energy balance and are linked to obesity and depression.On average,according to research,its 6-month weight loss results from research trials resulted in a weight loss of around 25 pounds.
Benefits:
Tesofensine for Weight Loss
Since discovering its ability to suppress appetite and aid in fat oxidation,researchers have diligently investigated the tesofensine obesity treatment.
2.Tesofensine for Depression
According to research,tesofensine may be helpful for depression.Research demonstrates that stress can decrease BDNF levels in the brain –
that is responsible for stimulating neuron growth and easing symptoms in those with depression and cognitive decline.When this exposure to stress becomes chronic and prolonged,atrophy of the hippocampus can occur.This change in the structure of the hippocampus has been linked to depression.
3.Tesofensine for Alzheimer¡¯s
While researchers may have abandoned the use of tesofensine in the treatment of Alzheimer¡¯s and Parkinson¡¯s,there¡¯s still enough evidence to show the compound boasts beneficial effects on memory and cognition.Despite the dopamine-boosting effects being too small to have a great impact on these neurological diseases,some scientists are still interested in harnessing the peptide¡¯s cognitive-enhancing abilities.
As previously mentioned,tesofensine peptide can increase BDNF levels.This,in turn,can help boost cell survival and reproduction.Experts are convinced this compound may be helpful for a range of conditions,including depression,obsessive-compulsive disorder,and Alzheimer¡¯s.
4.Tesofensine for Pain Management
While research is limited on these effects,there is evidence to suggest that this anti-depressant may be able to help when it comes to managing pain.Thanks to dopamine-boosting agents,tesofensine may aid in quelling pain.Of course,the current research focus is on its ability to boost weight loss.That said,scientists do believe they¡¯ll find more benefits of tesofensine the more they investigate the compound. |
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medical use
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Molecular Weight:328.28
Boiling Point: 396.6¡¾42.0 ¡ÆC
Color: White powderMolecular |
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pharmaceutical |
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AASraw/Aea.ltd
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+13204026693 |
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| E-mail |
King@aea.ltd
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FLAT/RM C1 4/F SUMMIT BUILDING 30 MAN YUE STREET HUNG HOM,HONG KONG,CHINA |
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