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| Doxorubicin hydrochloride |
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| Orange-Red Crystalline Solid |
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| 25316-40-9 |
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Usage£º Used as an antineoplastic
Usage£º Strong fluorescent dye intercalating into DNA. Antitumour antibiotic. Effect of adriamycin on heart mitochondrial DNA. Inhibitor of reverse transcriptase and RNA polymerase
immunosuppressive agent.
Usage£º Antibacterial
DNA intercalant
Usage£º Doxorubicin hydrochloride (adriamycin hydrochloride) is an antitumour agent that has been formulated as a salt to achieve higher water solubility. While the salt shares the same pharmacological properties as doxorubicin free base, its greater water solubility may offer advantages in some in vitro applications. Physicochemical properties and chromatographic behaviour will depend on whether the pH is buffered. In non-pH controlled systems the free base and salt may behave differently. |
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Doxorubicin hydrochloride
Product Name: Doxorubicin hydrochloride
Synonyms: ADRIACIN
ADRIBLASTINA
ADRIBLASTINA HYDROCHLORIDE
ADRIAMYCIN HCL
ADRIAMYCIN HYDROCHLORIDE
(8s-cis)-10-[(3-amino-2,3,6-trideoxy-alpha-l-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxynaphthacene-5,12-dione hydrochloride
14-HYDROXYDAUNOMYCIN HCL
14-HYDROXYDAUNOMYCIN HYDROCHLORIDE
CAS: 25316-40-9
MF: C27H30ClNO11
MW: 579.98
EINECS: 246-818-3
Chemical Properties£º Orange-Red Crystalline Solid
Usage£º Used as an antineoplastic
Usage£º Strong fluorescent dye intercalating into DNA. Antitumour antibiotic. Effect of adriamycin on heart mitochondrial DNA. Inhibitor of reverse transcriptase and RNA polymerase
immunosuppressive agent.
Usage£º Antibacterial
DNA intercalant
Usage£º Doxorubicin hydrochloride (adriamycin hydrochloride) is an antitumour agent that has been formulated as a salt to achieve higher water solubility. While the salt shares the same pharmacological properties as doxorubicin free base, its greater water solubility may offer advantages in some in vitro applications. Physicochemical properties and chromatographic behaviour will depend on whether the pH is buffered. In non-pH controlled systems the free base and salt may behave differently. |
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