Chemical Information Overview  |  Chemical Product  |  Chemical Raw Material  |  Chemical Company
Omeprazole
pharmaceutical
pharmaceutical
Omeprazole

CAS: 73590-58-6

Assay: 98.5% min. CP

Packing: 20Kg/cardboard drum

MF: C17H19N3O3S

MW: 345.42

Character: White Crystalline Solid. mp 156¡ÆC. solubility H2O: 0.5 mg/mL

Usage: Binds covalently to proton pump. It inhibits gastric secretion. Used as an anttiulcerative pharmaceutical raw materials.

Biological Activity: H + ,K + -ATPase inhibitor (IC 50 = 5.8 ¥ì M) that displays antisecretory and antiulcer activity. Inhibits gastric acid secretion (IC 50 = 0.16 ¥ì M for histamine-induced acid formation) and reduces gastric lesion formation induced by a variety of ulcerative stimuli. Antibacteral against Helicobacter pylori in vitro . Also inhibits CYP2C19, CYP2C9 and CYP3A (K i values are 3.1, 40.1 and 84.4 ¥ì M respectively) and blocks swelling-dependent chloride channels (ICIswell).

Industrial field pharmaceutical
HUBEI YUANCHENG GOGNCHUANG TECHNOLOGY CO.,LTD
Phone 86-027-88081553
Fax 86-027-88081553976
Homepage www.yccreate.com
E-mail ycgl15@yccreate.com
Address 496#zhongshan Road,Wuchang,Wuhan,China
There are no existing companies to distribute selected chemical product